5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid - Names and Identifiers
Name | 1,4-DIHYDRO-5-METHOXYCARBONYL-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC ACID
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Synonyms | 1,4-DHPCOOH Lercanidipine mainring 1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NTIROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID MONOMET Methylhydrogen1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate Methyl hydrogen 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate 5-Methoxycarbonyl-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydrpyridine-3-Carboxylic Acid 1,4-DIHYDRO-5-METHOXYCARBONYL-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC ACID 2,6-DiMethyl-5-Methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydorpyridine-3-carboxylic acid 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl ester 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl ester 2,6-DIMETHYL-5-METHOXY CARBONYL-4-(3-NITRO-PHENYL)-1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydroxypyridine-3-carboxylic acid 5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid 2,6-Dimethyl-5-Methoxycarbonyl-4-(3-Nitrophenyl)-1,4-Dihydordropyridine-3-Carboxylic Acid 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl) -3,5-pyridinedicarboxylic acid,monomethylester rac-1,4-Dihydro-5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic Acid
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CAS | 74936-72-4
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EINECS | 278-034-2 |
InChI | InChI=1/C16H16N2O6/c1-8-12(15(19)20)14(13(9(2)17-8)16(21)24-3)10-5-4-6-11(7-10)18(22)23/h4-7,14,17H,1-3H3,(H,19,20) |
5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid - Physico-chemical Properties
Molecular Formula | C16H16N2O6
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Molar Mass | 332.31 |
Density | 1.345±0.06 g/cm3(Predicted) |
Melting Point | 200-202?C |
Boling Point | 505.0±50.0 °C(Predicted) |
Flash Point | 259.2°C |
Solubility | DMSO (Sparingly), Methanol (Slightly, Heated) |
Vapor Presure | 5.1E-11mmHg at 25°C |
Appearance | Solid |
Color | Pale Yellow to Light Yellow |
pKa | 1.66±0.70(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.587 |
5-(methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid - Introduction
1.6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC ACID is an organic compound whose chemical formula is C18H19N3O6.
Nature:
-Appearance: This compound is a white or light yellow crystalline powder.
-Solubility: It is soluble in common organic solvents, such as acetone, ethanol and dichloromethane.
-Melting point: Its melting point is about 165-167 degrees Celsius.
Use:
- 1, 6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3-CARBOXYLIC ACID is an organic synthesis intermediate used in the synthesis of drugs, dyes and pesticides.
-It can be used as a precursor of anti-cancer drugs and anti-inflammatory drugs.
Preparation Method:
A common preparation method is obtained by reacting 2,6-dimethyl-4-carbonyl-3-carboxylic acid aniline with nitrobenzoic acid. A particular synthetic route will have multiple steps and reactions involving a variety of organic reagents and conditions.
Safety Information:
-Due to the lack of specific safety data, it should be regarded as a toxic and corrosive substance, and proper laboratory safety operations must be observed.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats when handling and handling the compound.
-Please store and handle the compound in accordance with the recommendations on the safety data sheet (MSDS).
Last Update:2024-04-09 19:05:52